Biosafety standards for working with Crimean-Congo hemorrhagic fever virus.
نویسندگان
چکیده
In countries from which Crimean-Congo haemorrhagic fever (CCHF) is absent, the causative virus, CCHF virus (CCHFV), is classified as a hazard group 4 agent and handled in containment level (CL)-4. In contrast, most endemic countries out of necessity have had to perform diagnostic tests under biosafety level (BSL)-2 or -3 conditions. In particular, Turkey and several of the Balkan countries have safely processed more than 100 000 samples over many years in BSL-2 laboratories. It is therefore advocated that biosafety requirements for CCHF diagnostic procedures should be revised, to allow the tests required to be performed under enhanced BSL-2 conditions with appropriate biosafety laboratory equipment and personal protective equipment used according to standardized protocols in the countries affected. Downgrading of CCHFV research work from CL-4, BSL-4 to CL-3, BSL-3 should also be considered.
منابع مشابه
A virus-like particle system identifies the endonuclease domain of Crimean-Congo hemorrhagic fever virus.
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ورودعنوان ژورنال:
- The Journal of general virology
دوره 97 11 شماره
صفحات -
تاریخ انتشار 2016